This article describes a scientific study that outlines a new method for producing silver nanoparticles capped with tartaric acid. The study conducted a comprehensive characterization of the nanoparticles using various techniques, including UV/Vis and FTIR spectroscopy, SEM, DLS, and Zetasizer. The results showed that the nanoparticles had a controlled size, well-dispersed, spherical shape, and a z-average size distribution of 79.20 nm, with a surface charge of -28.2 mV. The study also evaluated the antimicrobial and antioxidant activity of the nanoparticles against various bacteria and the DPPH free radical. The findings show that the nanoparticles exhibited significant synergistic effects with antibiotics, enhancing their antibacterial activity against studied microorganisms. Additionally, the capped nanoparticles demonstrated noteworthy antioxidant activity, suggesting their potential application in biomedical sciences. Overall, the study concludes that tartaric acid-capped silver nanoparticles have potential therapeutic applications and can be used in combination with antibiotics.
Author(s) Details:
Irshad Begum,
Department of Chemistry, University of Karachi, Karachi 75270, Pakistan.
Sana Shamim,
Department of Pharmaceutical Chemistry, Dow College of Pharmacy (DCOP), Faculty of Pharmaceutical Sciences, Dow University of Health Sciences (DUHS), Karachi 75270, Pakistan.
Please see the link here: https://stm.bookpi.org/ACPR-V4/article/view/13006
Keywords: Silver nanoparticles, capped, tartaric acid, one pot synthesis, antibiotics, antioxidant